diff --git a/packages/n/nifti/xmake.lua b/packages/n/nifti/xmake.lua
new file mode 100644
index 000000000..540de83cc
--- /dev/null
+++ b/packages/n/nifti/xmake.lua
@@ -0,0 +1,52 @@
+package("nifti")
+    set_homepage("https://github.com/NIFTI-Imaging/nifti_clib")
+    set_description("C libraries for NIFTI support")
+
+    add_urls("https://github.com/NIFTI-Imaging/nifti_clib.git")
+    add_versions("2024.01.25", "f24bec503f1a5d501c0413c1bb8aa3d6e04aebda")
+
+    add_configs("nifti2", {description = "Build nifti2.", default = false, type = "boolean"})
+    add_configs("cifti",  {description = "Build cifti.",  default = false, type = "boolean"})
+    add_configs("fslio",  {description = "Build fslio.",  default = false, type = "boolean"})
+    add_configs("tools",  {description = "Build tools.",  default = false, type = "boolean"})
+
+    add_deps("cmake")
+    add_deps("zlib")
+
+    on_load(function (package)
+        if package:config("cifti") then
+            package:add("deps", "expat")
+        end
+    end)
+
+    on_install("!cross and !wasm", function (package)
+        local configs = {
+            "-DBUILD_TESTING=OFF",
+            "-DNIFTI_INSTALL_NO_DOCS=ON",
+            "-DNIFTI_INSTALL_LIBRARY_DIR=" .. path.unix(package:installdir("lib"))
+        }
+        table.insert(configs, "-DCMAKE_BUILD_TYPE=" .. (package:is_debug() and "Debug" or "Release"))
+        table.insert(configs, "-DBUILD_SHARED_LIBS=" .. (package:config("shared") and "ON" or "OFF"))
+        if package:config("shared") and package:is_plat("windows") then
+            table.insert(configs, "-DCMAKE_WINDOWS_EXPORT_ALL_SYMBOLS=ON")
+            io.replace("nifticdf/nifticdf.h", "extern char const * const inam[];", "__declspec(dllimport) char const * const inam[];", {plain = true})
+        end
+
+        table.insert(configs, "-DUSE_NIFTI2_CODE=" .. (package:config("nifti2") and "ON" or "OFF"))
+        table.insert(configs, "-DUSE_CIFTI_CODE=" .. (package:config("cifti") and "ON" or "OFF"))
+        table.insert(configs, "-DUSE_FSL_CODE=" .. (package:config("fslio") and "ON" or "OFF"))
+        table.insert(configs, "-DNIFTI_BUILD_APPLICATIONS=" .. (package:config("tools") and "ON" or "OFF"))
+
+        local cxflags
+        if package:config("cifti") then
+            cxflags = "-DXML_STATIC"
+        end
+        import("package.tools.cmake").install(package, configs, {cxflags = cxflags, packagedeps = "zlib"})
+        if package:config("tools") then
+            package:addenv("PATH", "bin")
+        end
+    end)
+
+    on_test(function (package)
+        assert(package:has_cfuncs("nifti_stat2cdf", {includes = "nifti/nifticdf.h"}))
+    end)