diff --git a/src/google/protobuf/io/coded_stream.h b/src/google/protobuf/io/coded_stream.h
index 961c1a3f36..ad351dc3ae 100644
--- a/src/google/protobuf/io/coded_stream.h
+++ b/src/google/protobuf/io/coded_stream.h
@@ -112,8 +112,8 @@
 #include <string>
 #include <utility>
 #ifdef _MSC_VER
-  #if defined(_M_IX86) && \
-      !defined(PROTOBUF_DISABLE_LITTLE_ENDIAN_OPT_FOR_TEST)
+  // Assuming windows is always little-endian.
+  #if !defined(PROTOBUF_DISABLE_LITTLE_ENDIAN_OPT_FOR_TEST)
     #define PROTOBUF_LITTLE_ENDIAN 1
   #endif
   #if _MSC_VER >= 1300