Add some supporting documentation regarding Closure for those unfamiliar., Also substantiate details for "files in this directory" - including them all will result in a project that does not compile as some are used for test cases and aren't part of the core library.
At a high level, closurebuilder.py can walk dependencies, and compile your code, and all dependencies for Protobuf into a single .js file. Using depsbuilder.py to generate a dependency file can also be considered for non-production dev environments.