diff --git a/.bcr/presubmit.yml b/.bcr/presubmit.yml
index 4f47bf75f7..bd9ba1d379 100644
--- a/.bcr/presubmit.yml
+++ b/.bcr/presubmit.yml
@@ -13,6 +13,7 @@ tasks:
     build_targets:
     - '@protobuf//:protobuf'
     - '@protobuf//:protobuf_lite'
+    - '@protobuf//:protobuf_python'
     - '@protobuf//:protobuf_rust'
     - '@protobuf//:protoc'
     - '@protobuf//:test_messages_proto2_cc_proto'
@@ -21,7 +22,6 @@ tasks:
 bcr_test_module:
   module_path: "examples"
   matrix:
-
     platform: ["debian10", "macos", "ubuntu2004", "windows"]
     bazel: [6.x, 7.x]
   tasks:
diff --git a/MODULE.bazel b/MODULE.bazel
index 93dca5dd02..46207904a5 100644
--- a/MODULE.bazel
+++ b/MODULE.bazel
@@ -28,6 +28,33 @@ bazel_dep(name = "zlib", version = "1.2.11")
 # TODO: remove after toolchain types are moved to protobuf
 bazel_dep(name = "rules_proto", version = "4.0.0")
 
+SUPPORTED_PYTHON_VERSIONS = [
+    "3.8",
+    "3.9",
+    "3.10",
+    "3.11",
+    "3.12",
+]
+python = use_extension("@rules_python//python/extensions:python.bzl", "python")
+[
+    python.toolchain(
+        is_default = python_version == SUPPORTED_PYTHON_VERSIONS[-1],
+        python_version = python_version,
+    )
+    for python_version in SUPPORTED_PYTHON_VERSIONS
+]
+use_repo(python, system_python = "python_{}".format(SUPPORTED_PYTHON_VERSIONS[-1].replace(".", "_")))
+pip = use_extension("@rules_python//python/extensions:pip.bzl", "pip")
+[
+    pip.parse(
+        hub_name = "pip_deps",
+        python_version = python_version,
+        requirements_lock = "//python:requirements.txt",
+    )
+    for python_version in SUPPORTED_PYTHON_VERSIONS
+]
+use_repo(pip, "pip_deps")
+
 rust = use_extension("@rules_rust//rust:extensions.bzl", "rust")
 rust.toolchain(edition = "2021")
 use_repo(rust, "rust_toolchains")