diff --git a/mesonbuild/modules/gnome.py b/mesonbuild/modules/gnome.py
index c91cda66f..ff4c681b5 100644
--- a/mesonbuild/modules/gnome.py
+++ b/mesonbuild/modules/gnome.py
@@ -35,6 +35,7 @@ from ..mesonlib import (
 from ..dependencies import Dependency, PkgConfigDependency, InternalDependency
 from ..interpreterbase import noPosargs, noKwargs, permittedKwargs, FeatureNew, FeatureNewKwargs, FeatureDeprecatedKwargs
 from ..programs import ExternalProgram, OverrideProgram
+from ..build import CustomTarget, CustomTargetIndex, GeneratedList
 
 if T.TYPE_CHECKING:
     from ..compilers import Compiler
@@ -709,8 +710,9 @@ class GnomeModule(ExtensionModule):
 
         return gir_filelist_filename
 
-    def _make_gir_target(self, state, girfile, scan_command, depends, kwargs):
-        scankwargs = {'output': girfile,
+    def _make_gir_target(self, state, girfile, scan_command, generated_files, depends, kwargs):
+        scankwargs = {'input': generated_files,
+                      'output': girfile,
                       'command': scan_command,
                       'depends': depends}
 
@@ -724,8 +726,9 @@ class GnomeModule(ExtensionModule):
 
         return GirTarget(girfile, state.subdir, state.subproject, scankwargs)
 
-    def _make_typelib_target(self, state, typelib_output, typelib_cmd, kwargs):
+    def _make_typelib_target(self, state, typelib_output, typelib_cmd, generated_files, kwargs):
         typelib_kwargs = {
+            'input': generated_files,
             'output': typelib_output,
             'command': typelib_cmd,
         }
@@ -801,7 +804,7 @@ class GnomeModule(ExtensionModule):
                       'export_packages', 'includes', 'dependencies', 'link_with', 'include_directories',
                       'install', 'install_dir_gir', 'install_dir_typelib', 'extra_args',
                       'packages', 'header', 'build_by_default', 'fatal_warnings'})
-    def generate_gir(self, state, args, kwargs):
+    def generate_gir(self, state, args, kwargs: T.Dict[str, T.Any]):
         if not args:
             raise MesonException('generate_gir takes at least one argument')
         if kwargs.get('install_dir'):
@@ -881,7 +884,9 @@ class GnomeModule(ExtensionModule):
         if fatal_warnings:
             scan_command.append('--warn-error')
 
-        scan_target = self._make_gir_target(state, girfile, scan_command, depends, kwargs)
+        generated_files = [unholder(f) for f in libsources if isinstance(unholder(f), (GeneratedList, CustomTarget, CustomTargetIndex))]
+
+        scan_target = self._make_gir_target(state, girfile, scan_command, generated_files, depends, kwargs)
 
         typelib_output = f'{ns}-{nsversion}.typelib'
         typelib_cmd = [gicompiler, scan_target, '--output', '@OUTPUT@']
@@ -890,7 +895,8 @@ class GnomeModule(ExtensionModule):
         for incdir in typelib_includes:
             typelib_cmd += ["--includedir=" + incdir]
 
-        typelib_target = self._make_typelib_target(state, typelib_output, typelib_cmd, kwargs)
+        typelib_target = self._make_typelib_target(state, typelib_output, typelib_cmd, generated_files, kwargs)
+
         self._devenv_append('GI_TYPELIB_PATH', os.path.join(state.environment.get_build_dir(), state.subdir))
 
         rv = [scan_target, typelib_target]
diff --git a/test cases/frameworks/7 gnome/gir/copy.py b/test cases/frameworks/7 gnome/gir/copy.py
new file mode 100755
index 000000000..fa70145b5
--- /dev/null
+++ b/test cases/frameworks/7 gnome/gir/copy.py	
@@ -0,0 +1,18 @@
+#!/usr/bin/env python3
+# SPDX-License-Identifier: Apache-2.0
+# Copyright © 2021 Intel Corproation
+
+import argparse
+import shutil
+
+def main() -> None:
+    parser = argparse.ArgumentParser()
+    parser.add_argument('src')
+    parser.add_argument('dest')
+    args = parser.parse_args()
+
+    shutil.copy(args.src, args.dest)
+
+
+if __name__ == "__main__":
+    main()
diff --git a/test cases/frameworks/7 gnome/gir/meson.build b/test cases/frameworks/7 gnome/gir/meson.build
index b1e0fa1fe..64c49f729 100644
--- a/test cases/frameworks/7 gnome/gir/meson.build	
+++ b/test cases/frameworks/7 gnome/gir/meson.build	
@@ -3,6 +3,14 @@ subdir('dep1')
 libsources = ['meson-sample.c', 'meson-sample.h']
 lib2sources = ['meson-sample2.c', 'meson-sample2.h']
 
+gen_source = custom_target(
+  'meson_smaple3.h',
+  input : 'meson-sample.h',
+  output : 'meson-sample3.h',
+  command : [find_program('copy.py'), '@INPUT@', '@OUTPUT@'],
+  build_by_default : false,  # this will force a race condition if one exists
+)
+
 girlib = shared_library(
   'gir_lib',
   sources : libsources,
@@ -28,7 +36,7 @@ fake_dep = dependency('no-way-this-exists', required: false)
 
 gnome.generate_gir(
   girlib, girlib2,
-  sources : libsources + lib2sources,
+  sources : [libsources, lib2sources, gen_source],
   nsversion : '1.0',
   namespace : 'Meson',
   symbol_prefix : 'meson',