diff --git a/test cases/cython/2 generated sources/meson.build b/test cases/cython/2 generated sources/meson.build
index cffddd38e..498e31908 100644
--- a/test cases/cython/2 generated sources/meson.build	
+++ b/test cases/cython/2 generated sources/meson.build	
@@ -90,6 +90,11 @@ includestuff_ext = py3.extension_module(
   dependencies: stuff_pxi_dep
 )
 
+simpleinclude_ext = py3.extension_module(
+  'simpleinclude',
+  'simpleinclude.pyx',
+)
+
 subdir('libdir')
 
 test(
diff --git a/test cases/cython/2 generated sources/simpleinclude.pyx b/test cases/cython/2 generated sources/simpleinclude.pyx
new file mode 100644
index 000000000..c110f7517
--- /dev/null
+++ b/test cases/cython/2 generated sources/simpleinclude.pyx	
@@ -0,0 +1 @@
+include "simplestuff.pxi"
diff --git a/test cases/cython/2 generated sources/simplestuff.pxi b/test cases/cython/2 generated sources/simplestuff.pxi
new file mode 100644
index 000000000..264521651
--- /dev/null
+++ b/test cases/cython/2 generated sources/simplestuff.pxi	
@@ -0,0 +1,2 @@
+def func2():
+    print("Hello world")
diff --git a/unittests/allplatformstests.py b/unittests/allplatformstests.py
index ac60907a5..5f4af3b24 100644
--- a/unittests/allplatformstests.py
+++ b/unittests/allplatformstests.py
@@ -859,6 +859,27 @@ class AllPlatformTests(BasePlatformTests):
         name = "/".join(name)  # Glue list into a string
         self.build(target=name)
 
+    def test_build_pyx_depfiles(self):
+        # building regularly and then touching a depfile dependency should rebuild
+        testdir = os.path.join("test cases/cython", '2 generated sources')
+        env = get_fake_env(testdir, self.builddir, self.prefix)
+        try:
+            cython = detect_compiler_for(env, "cython", MachineChoice.HOST)
+            if not version_compare(cython.version, '>=0.29.33'):
+                raise SkipTest('Cython is too old')
+        except EnvironmentException:
+            raise SkipTest("Cython is not installed")
+        self.init(testdir)
+
+        targets = self.introspect('--targets')
+        for target in targets:
+            if target['name'].startswith('simpleinclude'):
+                name = target['name']
+        self.build()
+        self.utime(os.path.join(testdir, 'simplestuff.pxi'))
+        self.assertBuildRelinkedOnlyTarget(name)
+
+
     def test_internal_include_order(self):
         if mesonbuild.environment.detect_msys2_arch() and ('MESON_RSP_THRESHOLD' in os.environ):
             raise SkipTest('Test does not yet support gcc rsp files on msys2')