- [RxDock](https://gitlab.com/rxdock/rxdock), a protein-ligand docking software designed for high throughput virtual screening (fork of rDock)
- [scrcpy](https://github.com/Genymobile/scrcpy), a cross platform application that provides display and control of Android devices connected on USB or over TCP/IP
- [Sequeler](https://github.com/Alecaddd/sequeler), a friendly SQL client for Linux, built with Vala and Gtk
- [Siril](https://gitlab.com/free-astro/siril), an image processing software for amateur astronomy
- [SSHFS](https://github.com/libfuse/sshfs), allows you to mount a remote filesystem using SFTP
- [sway](https://github.com/swaywm/sway), i3-compatible Wayland compositor
- [Sysprof](https://git.gnome.org/browse/sysprof), a profiling tool