diff --git a/Makefile b/Makefile
index e47879b7f9d..85002fb8f41 100644
--- a/Makefile
+++ b/Makefile
@@ -2184,8 +2184,6 @@ test_cxx: buildtests_cxx
 	$(Q) $(BINDIR)/$(CONFIG)/byte_buffer_test || ( echo test byte_buffer_test failed ; exit 1 )
 	$(E) "[RUN]     Testing byte_stream_test"
 	$(Q) $(BINDIR)/$(CONFIG)/byte_stream_test || ( echo test byte_stream_test failed ; exit 1 )
-	$(E) "[RUN]     Testing cancel_ares_query_test"
-	$(Q) $(BINDIR)/$(CONFIG)/cancel_ares_query_test || ( echo test cancel_ares_query_test failed ; exit 1 )
 	$(E) "[RUN]     Testing channel_arguments_test"
 	$(Q) $(BINDIR)/$(CONFIG)/channel_arguments_test || ( echo test channel_arguments_test failed ; exit 1 )
 	$(E) "[RUN]     Testing channel_filter_test"
diff --git a/build_autogenerated.yaml b/build_autogenerated.yaml
index d65be68d6c9..5d0f6d219ba 100644
--- a/build_autogenerated.yaml
+++ b/build_autogenerated.yaml
@@ -5348,6 +5348,7 @@ targets:
 - name: cancel_ares_query_test
   gtest: true
   build: test
+  run: false
   language: c++
   headers:
   - test/core/end2end/cq_verifier.h
diff --git a/test/cpp/naming/BUILD b/test/cpp/naming/BUILD
index b35c37c0349..dd2dac7ee12 100644
--- a/test/cpp/naming/BUILD
+++ b/test/cpp/naming/BUILD
@@ -38,6 +38,7 @@ grpc_cc_test(
     name = "cancel_ares_query_test",
     srcs = ["cancel_ares_query_test.cc"],
     external_deps = ["gtest"],
+    flaky = True,  # TODO(b/157516105)
     deps = [
         ":dns_test_util",
         "//:gpr",
diff --git a/tools/run_tests/generated/tests.json b/tools/run_tests/generated/tests.json
index b395729d7c7..632c0bb1130 100644
--- a/tools/run_tests/generated/tests.json
+++ b/tools/run_tests/generated/tests.json
@@ -3905,30 +3905,6 @@
     ], 
     "uses_polling": false
   }, 
-  {
-    "args": [], 
-    "benchmark": false, 
-    "ci_platforms": [
-      "linux", 
-      "mac", 
-      "posix", 
-      "windows"
-    ], 
-    "cpu_cost": 1.0, 
-    "exclude_configs": [], 
-    "exclude_iomgrs": [], 
-    "flaky": false, 
-    "gtest": true, 
-    "language": "c++", 
-    "name": "cancel_ares_query_test", 
-    "platforms": [
-      "linux", 
-      "mac", 
-      "posix", 
-      "windows"
-    ], 
-    "uses_polling": true
-  }, 
   {
     "args": [], 
     "benchmark": false,