diff --git a/BUILD b/BUILD
index 045eeab8089..9702615098f 100644
--- a/BUILD
+++ b/BUILD
@@ -2759,7 +2759,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -2807,7 +2807,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -2898,7 +2898,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -2985,7 +2985,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -3024,7 +3024,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -3103,7 +3103,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -3163,7 +3163,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
@@ -3238,7 +3238,6 @@ grpc_cc_library(
         "src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/api/http.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c",
-        "src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.c",
@@ -3250,7 +3249,6 @@ grpc_cc_library(
         "src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/api/http.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.h",
-        "src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.h",
@@ -3260,7 +3258,7 @@ grpc_cc_library(
     ],
     external_deps = [
         "upb_lib",
-        "upb_lib_descriptor",
+        "upb_lib_descriptor_reflection",
         "upb_textformat_lib",
     ],
     language = "c++",
diff --git a/BUILD.gn b/BUILD.gn
index 7923887e7a7..1eefe41a37a 100644
--- a/BUILD.gn
+++ b/BUILD.gn
@@ -685,8 +685,6 @@ config("grpc_config") {
         "src/core/ext/upbdefs-generated/google/api/http.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.h",
-        "src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c",
-        "src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c",
         "src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.h",
         "src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c",
diff --git a/CMakeLists.txt b/CMakeLists.txt
index 4eaed7e39d6..64a4a9076e5 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -1695,7 +1695,6 @@ add_library(grpc
   src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.c
   src/core/ext/upbdefs-generated/google/api/http.upbdefs.c
   src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c
-  src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c
   src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c
   src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c
   src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.c
diff --git a/Makefile b/Makefile
index c9dd0dad691..92b71ef0b0a 100644
--- a/Makefile
+++ b/Makefile
@@ -1283,7 +1283,6 @@ LIBGRPC_SRC = \
     src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.c \
     src/core/ext/upbdefs-generated/google/api/http.upbdefs.c \
     src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c \
-    src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c \
     src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c \
     src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c \
     src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.c \
diff --git a/bazel/grpc_deps.bzl b/bazel/grpc_deps.bzl
index 266967e6eda..a8fc73539da 100644
--- a/bazel/grpc_deps.bzl
+++ b/bazel/grpc_deps.bzl
@@ -16,6 +16,11 @@ def grpc_deps():
         actual = "@upb//:descriptor_upb_proto",
     )
 
+    native.bind(
+        name = "upb_lib_descriptor_reflection",
+        actual = "@upb//:descriptor_upb_proto_reflection",
+    )
+
     native.bind(
         name = "upb_textformat_lib",
         actual = "@upb//:textformat",
diff --git a/build_autogenerated.yaml b/build_autogenerated.yaml
index 785f6ec656e..45dd397425d 100644
--- a/build_autogenerated.yaml
+++ b/build_autogenerated.yaml
@@ -612,7 +612,6 @@ libs:
   - src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.h
   - src/core/ext/upbdefs-generated/google/api/http.upbdefs.h
   - src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.h
-  - src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.h
   - src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.h
   - src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.h
   - src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.h
@@ -1116,7 +1115,6 @@ libs:
   - src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.c
   - src/core/ext/upbdefs-generated/google/api/http.upbdefs.c
   - src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c
-  - src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c
   - src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c
   - src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c
   - src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.c
diff --git a/grpc.gyp b/grpc.gyp
index df60c79db83..d8a2616c233 100644
--- a/grpc.gyp
+++ b/grpc.gyp
@@ -702,7 +702,6 @@
         'src/core/ext/upbdefs-generated/google/api/annotations.upbdefs.c',
         'src/core/ext/upbdefs-generated/google/api/http.upbdefs.c',
         'src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c',
-        'src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c',
         'src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c',
         'src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c',
         'src/core/ext/upbdefs-generated/google/protobuf/struct.upbdefs.c',
diff --git a/tools/doxygen/Doxyfile.c++.internal b/tools/doxygen/Doxyfile.c++.internal
index e2b368289fa..575aedde096 100644
--- a/tools/doxygen/Doxyfile.c++.internal
+++ b/tools/doxygen/Doxyfile.c++.internal
@@ -1515,8 +1515,6 @@ src/core/ext/upbdefs-generated/google/api/http.upbdefs.c \
 src/core/ext/upbdefs-generated/google/api/http.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c \
 src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.h \
-src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c \
-src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c \
 src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c \
diff --git a/tools/doxygen/Doxyfile.core.internal b/tools/doxygen/Doxyfile.core.internal
index 13ab803eebb..891a3c12d84 100644
--- a/tools/doxygen/Doxyfile.core.internal
+++ b/tools/doxygen/Doxyfile.core.internal
@@ -1351,8 +1351,6 @@ src/core/ext/upbdefs-generated/google/api/http.upbdefs.c \
 src/core/ext/upbdefs-generated/google/api/http.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.c \
 src/core/ext/upbdefs-generated/google/protobuf/any.upbdefs.h \
-src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.c \
-src/core/ext/upbdefs-generated/google/protobuf/descriptor.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.c \
 src/core/ext/upbdefs-generated/google/protobuf/duration.upbdefs.h \
 src/core/ext/upbdefs-generated/google/protobuf/empty.upbdefs.c \