diff --git a/tools/run_tests/build_python.sh b/tools/run_tests/build_python.sh
index d2ff1c6b53c..0a73353ce5e 100755
--- a/tools/run_tests/build_python.sh
+++ b/tools/run_tests/build_python.sh
@@ -170,8 +170,7 @@ pip_install_dir() {
 }
 
 $VENV_PYTHON -m pip install --upgrade pip
-# TODO(https://github.com/pypa/setuptools/issues/709) get the latest setuptools
-$VENV_PYTHON -m pip install setuptools==25.1.1
+$VENV_PYTHON -m pip install setuptools
 $VENV_PYTHON -m pip install cython
 pip_install_dir $ROOT
 $VENV_PYTHON $ROOT/tools/distrib/python/make_grpcio_tools.py