diff --git a/grpc.def b/grpc.def
index e220212fc67..ddc6440f34f 100644
--- a/grpc.def
+++ b/grpc.def
@@ -233,7 +233,6 @@ EXPORTS
     gpr_log
     gpr_should_log
     gpr_log_verbosity_init
-    gpr_set_log_function
     gpr_format_message
     gpr_strdup
     gpr_asprintf
diff --git a/include/grpc/support/log.h b/include/grpc/support/log.h
index 263b69f5203..88e7628e0cc 100644
--- a/include/grpc/support/log.h
+++ b/include/grpc/support/log.h
@@ -55,22 +55,6 @@ GPRAPI int gpr_should_log(gpr_log_severity severity);
 
 GPRAPI void gpr_log_verbosity_init(void);
 
-/** Log overrides: applications can use this API to intercept logging calls
-   and use their own implementations */
-
-struct gpr_log_func_args {
-  const char* file;
-  int line;
-  gpr_log_severity severity;
-  const char* message;
-};
-
-typedef struct gpr_log_func_args gpr_log_func_args;
-
-typedef void (*gpr_log_func)(gpr_log_func_args* args);
-
-GPRAPI void gpr_set_log_function(gpr_log_func deprecated_setting);
-
 #ifdef __cplusplus
 }
 #endif
diff --git a/src/core/util/log.cc b/src/core/util/log.cc
index 6726cde67d1..411f76a14cd 100644
--- a/src/core/util/log.cc
+++ b/src/core/util/log.cc
@@ -119,10 +119,3 @@ void gpr_log_verbosity_init(void) {
   }
 #endif  // GRPC_VERBOSITY_MACRO
 }
-
-void gpr_set_log_function([[maybe_unused]] gpr_log_func deprecated_setting) {
-  LOG(ERROR)
-      << "This function is deprecated. This function will be deleted in the "
-         "next gRPC release. You may create a new absl LogSink with similar "
-         "functionality. gRFC: https://github.com/grpc/proposal/pull/425 ";
-}
diff --git a/src/ruby/ext/grpc/rb_grpc_imports.generated.c b/src/ruby/ext/grpc/rb_grpc_imports.generated.c
index 01f66dbdc43..b0cfa9ce6b0 100644
--- a/src/ruby/ext/grpc/rb_grpc_imports.generated.c
+++ b/src/ruby/ext/grpc/rb_grpc_imports.generated.c
@@ -256,7 +256,6 @@ gpr_cpu_current_cpu_type gpr_cpu_current_cpu_import;
 gpr_log_type gpr_log_import;
 gpr_should_log_type gpr_should_log_import;
 gpr_log_verbosity_init_type gpr_log_verbosity_init_import;
-gpr_set_log_function_type gpr_set_log_function_import;
 gpr_format_message_type gpr_format_message_import;
 gpr_strdup_type gpr_strdup_import;
 gpr_asprintf_type gpr_asprintf_import;
@@ -542,7 +541,6 @@ void grpc_rb_load_imports(HMODULE library) {
   gpr_log_import = (gpr_log_type) GetProcAddress(library, "gpr_log");
   gpr_should_log_import = (gpr_should_log_type) GetProcAddress(library, "gpr_should_log");
   gpr_log_verbosity_init_import = (gpr_log_verbosity_init_type) GetProcAddress(library, "gpr_log_verbosity_init");
-  gpr_set_log_function_import = (gpr_set_log_function_type) GetProcAddress(library, "gpr_set_log_function");
   gpr_format_message_import = (gpr_format_message_type) GetProcAddress(library, "gpr_format_message");
   gpr_strdup_import = (gpr_strdup_type) GetProcAddress(library, "gpr_strdup");
   gpr_asprintf_import = (gpr_asprintf_type) GetProcAddress(library, "gpr_asprintf");
diff --git a/src/ruby/ext/grpc/rb_grpc_imports.generated.h b/src/ruby/ext/grpc/rb_grpc_imports.generated.h
index 48fe5f38e05..1b325a1a024 100644
--- a/src/ruby/ext/grpc/rb_grpc_imports.generated.h
+++ b/src/ruby/ext/grpc/rb_grpc_imports.generated.h
@@ -744,9 +744,6 @@ extern gpr_should_log_type gpr_should_log_import;
 typedef void(*gpr_log_verbosity_init_type)(void);
 extern gpr_log_verbosity_init_type gpr_log_verbosity_init_import;
 #define gpr_log_verbosity_init gpr_log_verbosity_init_import
-typedef void(*gpr_set_log_function_type)(gpr_log_func deprecated_setting);
-extern gpr_set_log_function_type gpr_set_log_function_import;
-#define gpr_set_log_function gpr_set_log_function_import
 typedef char*(*gpr_format_message_type)(int messageid);
 extern gpr_format_message_type gpr_format_message_import;
 #define gpr_format_message gpr_format_message_import