diff --git a/tools/distrib/sanitize.sh b/tools/distrib/sanitize.sh
index a31f1b86628..bc48ad50743 100755
--- a/tools/distrib/sanitize.sh
+++ b/tools/distrib/sanitize.sh
@@ -17,7 +17,6 @@ set -ex
 
 cd $(dirname $0)/../..
 
-tools/distrib/iwyu.sh || true
 tools/buildgen/generate_projects.sh
 tools/distrib/check_include_guards.py --fix
 tools/distrib/check_naked_includes.py --fix || true
diff --git a/tools/run_tests/run_tests_matrix.py b/tools/run_tests/run_tests_matrix.py
index cb346c90797..e6bd5e4e9ae 100755
--- a/tools/run_tests/run_tests_matrix.py
+++ b/tools/run_tests/run_tests_matrix.py
@@ -226,7 +226,7 @@ def _create_test_jobs(extra_args=[], inner_jobs=_DEFAULT_INNER_JOBS):
     test_jobs = []
     # sanity tests
     test_jobs += _generate_jobs(
-        languages=["sanity", "clang-tidy", "iwyu"],
+        languages=["sanity", "clang-tidy"],
         configs=["dbg"],
         platforms=["linux"],
         labels=["basictests"],
diff --git a/tools/run_tests/sanity/check_test_filtering.py b/tools/run_tests/sanity/check_test_filtering.py
index 3f2366f8c9d..5ceb4fa5019 100755
--- a/tools/run_tests/sanity/check_test_filtering.py
+++ b/tools/run_tests/sanity/check_test_filtering.py
@@ -37,7 +37,7 @@ _LIST_OF_LANGUAGE_LABELS = [
     "ruby",
 ]
 _LIST_OF_PLATFORM_LABELS = ["linux", "macos", "windows"]
-_LIST_OF_SANITY_TESTS = ["sanity", "clang-tidy", "iwyu"]
+_LIST_OF_SANITY_TESTS = ["sanity", "clang-tidy"]
 
 
 def has_sanity_tests(job):