diff --git a/requirements.bazel.txt b/requirements.bazel.txt
index b42c8f63bd7..0a26df5ac27 100644
--- a/requirements.bazel.txt
+++ b/requirements.bazel.txt
@@ -15,4 +15,3 @@ setuptools==44.1.1
 xds-protos==0.0.11
 opencensus==0.10.0
 opencensus-ext-stackdriver==0.8.0
-absl-py==1.4.0
diff --git a/src/python/grpcio_tests/setup.py b/src/python/grpcio_tests/setup.py
index 0cef4c2755e..8409dcc9519 100644
--- a/src/python/grpcio_tests/setup.py
+++ b/src/python/grpcio_tests/setup.py
@@ -47,7 +47,6 @@ INSTALL_REQUIRES = (
     "protobuf>=4.21.6rc1,!=4.22.0.*",
     "google-auth>=1.17.2",
     "requests>=2.14.2",
-    "absl-py>=1.4.0",
 )
 
 COMMAND_CLASS = {
diff --git a/src/python/grpcio_tests/tests/interop/BUILD.bazel b/src/python/grpcio_tests/tests/interop/BUILD.bazel
index 2d164847423..aa7e15544c4 100644
--- a/src/python/grpcio_tests/tests/interop/BUILD.bazel
+++ b/src/python/grpcio_tests/tests/interop/BUILD.bazel
@@ -94,7 +94,6 @@ py_library(
         "//src/proto/grpc/testing:py_test_proto",
         "//src/python/grpcio/grpc:grpcio",
         "//src/python/grpcio_tests/tests/unit:test_common",
-        requirement("absl-py"),
     ],
 )
 
diff --git a/src/python/grpcio_tests/tests/interop/server.py b/src/python/grpcio_tests/tests/interop/server.py
index 4fd0a4bde22..d51671ef8a9 100644
--- a/src/python/grpcio_tests/tests/interop/server.py
+++ b/src/python/grpcio_tests/tests/interop/server.py
@@ -13,11 +13,10 @@
 # limitations under the License.
 """The Python implementation of the GRPC interoperability test server."""
 
+import argparse
 from concurrent import futures
 import logging
 
-from absl import app
-from absl.flags import argparse_flags
 import grpc
 
 from src.proto.grpc.testing import test_pb2_grpc
@@ -29,8 +28,8 @@ logging.basicConfig()
 _LOGGER = logging.getLogger(__name__)
 
 
-def parse_interop_server_arguments(argv):
-    parser = argparse_flags.ArgumentParser()
+def parse_interop_server_arguments():
+    parser = argparse.ArgumentParser()
     parser.add_argument(
         "--port", type=int, required=True, help="the port on which to serve"
     )
@@ -46,7 +45,7 @@ def parse_interop_server_arguments(argv):
         type=resources.parse_bool,
         help="require an ALTS connection",
     )
-    return parser.parse_args(argv[1:])
+    return parser.parse_args()
 
 
 def get_server_credentials(use_tls):
@@ -58,7 +57,9 @@ def get_server_credentials(use_tls):
         return grpc.alts_server_credentials()
 
 
-def serve(args):
+def serve():
+    args = parse_interop_server_arguments()
+
     server = test_common.test_server()
     test_pb2_grpc.add_TestServiceServicer_to_server(
         service.TestService(), server
@@ -76,6 +77,4 @@ def serve(args):
 
 
 if __name__ == "__main__":
-    app.run(
-        serve, flags_parser=parse_interop_server_arguments
-    )
+    serve()
diff --git a/src/python/grpcio_tests/tests_aio/interop/server.py b/src/python/grpcio_tests/tests_aio/interop/server.py
index 3247bed26a8..7786a4206a6 100644
--- a/src/python/grpcio_tests/tests_aio/interop/server.py
+++ b/src/python/grpcio_tests/tests_aio/interop/server.py
@@ -16,7 +16,6 @@
 import argparse
 import asyncio
 import logging
-import sys
 
 import grpc
 
@@ -28,7 +27,9 @@ _LOGGER = logging.getLogger(__name__)
 _LOGGER.setLevel(logging.DEBUG)
 
 
-async def serve(args):
+async def serve():
+    args = interop_server_lib.parse_interop_server_arguments()
+
     if args.use_tls or args.use_alts:
         credentials = interop_server_lib.get_server_credentials(args.use_tls)
         address, server = await _test_server.start_test_server(
@@ -46,5 +47,4 @@ async def serve(args):
 
 
 if __name__ == "__main__":
-    args = interop_server_lib.parse_interop_server_arguments(sys.argv)
-    asyncio.get_event_loop().run_until_complete(serve(args))
+    asyncio.get_event_loop().run_until_complete(serve())
diff --git a/tools/run_tests/helper_scripts/build_python.sh b/tools/run_tests/helper_scripts/build_python.sh
index 72fc7d76b28..4f40fe7b438 100755
--- a/tools/run_tests/helper_scripts/build_python.sh
+++ b/tools/run_tests/helper_scripts/build_python.sh
@@ -209,7 +209,7 @@ pip_install_dir "$ROOT/src/python/grpcio_testing"
 # Build/install tests
 pip_install coverage==4.4 oauth2client==4.1.0 \
             google-auth>=1.17.2 requests==2.14.2 \
-            googleapis-common-protos>=1.5.5 rsa==4.0 absl-py==1.4.0
+            googleapis-common-protos>=1.5.5 rsa==4.0
 $VENV_PYTHON "$ROOT/src/python/grpcio_tests/setup.py" preprocess
 $VENV_PYTHON "$ROOT/src/python/grpcio_tests/setup.py" build_package_protos
 pip_install_dir "$ROOT/src/python/grpcio_tests"