diff --git a/Makefile b/Makefile
index 0bcd128cc95..01af1280092 100644
--- a/Makefile
+++ b/Makefile
@@ -2216,8 +2216,6 @@ test_cxx: buildtests_cxx
 	$(Q) $(BINDIR)/$(CONFIG)/client_channel_stress_test || ( echo test client_channel_stress_test failed ; exit 1 )
 	$(E) "[RUN]     Testing client_interceptors_end2end_test"
 	$(Q) $(BINDIR)/$(CONFIG)/client_interceptors_end2end_test || ( echo test client_interceptors_end2end_test failed ; exit 1 )
-	$(E) "[RUN]     Testing client_lb_end2end_test"
-	$(Q) $(BINDIR)/$(CONFIG)/client_lb_end2end_test || ( echo test client_lb_end2end_test failed ; exit 1 )
 	$(E) "[RUN]     Testing codegen_test_full"
 	$(Q) $(BINDIR)/$(CONFIG)/codegen_test_full || ( echo test codegen_test_full failed ; exit 1 )
 	$(E) "[RUN]     Testing codegen_test_minimal"
diff --git a/build_autogenerated.yaml b/build_autogenerated.yaml
index d28144e7f4c..c57d9605f51 100644
--- a/build_autogenerated.yaml
+++ b/build_autogenerated.yaml
@@ -5578,6 +5578,7 @@ targets:
 - name: client_lb_end2end_test
   gtest: true
   build: test
+  run: false
   language: c++
   headers:
   - test/core/util/test_lb_policies.h
diff --git a/test/cpp/end2end/BUILD b/test/cpp/end2end/BUILD
index 5bbee23deee..a20128dcc2d 100644
--- a/test/cpp/end2end/BUILD
+++ b/test/cpp/end2end/BUILD
@@ -439,6 +439,7 @@ grpc_cc_test(
     external_deps = [
         "gtest",
     ],
+    flaky = True,  # TODO(b/151315347)
     tags = ["no_windows"],  # TODO(jtattermusch): fix test on windows
     deps = [
         ":test_service_impl",
diff --git a/tools/run_tests/generated/tests.json b/tools/run_tests/generated/tests.json
index 469dfb43a19..32a7e1681cf 100644
--- a/tools/run_tests/generated/tests.json
+++ b/tools/run_tests/generated/tests.json
@@ -4195,28 +4195,6 @@
     ], 
     "uses_polling": true
   }, 
-  {
-    "args": [], 
-    "benchmark": false, 
-    "ci_platforms": [
-      "linux", 
-      "mac", 
-      "posix"
-    ], 
-    "cpu_cost": 1.0, 
-    "exclude_configs": [], 
-    "exclude_iomgrs": [], 
-    "flaky": false, 
-    "gtest": true, 
-    "language": "c++", 
-    "name": "client_lb_end2end_test", 
-    "platforms": [
-      "linux", 
-      "mac", 
-      "posix"
-    ], 
-    "uses_polling": true
-  }, 
   {
     "args": [], 
     "benchmark": false,