diff --git a/Rakefile b/Rakefile
index 1eac37dc557..0068a3b8e4f 100755
--- a/Rakefile
+++ b/Rakefile
@@ -23,6 +23,12 @@ end
 
 # Add the extension compiler task
 Rake::ExtensionTask.new('grpc_c', spec) do |ext|
+  unless RUBY_PLATFORM =~ /darwin/
+    # TODO: also set "no_native to true" for mac if possible. As is,
+    # "no_native" can only be set if the RUBY_PLATFORM doing
+    # cross-compilation is contained in the "ext.cross_platform" array.
+    ext.no_native = true
+  end
   ext.source_pattern = '**/*.{c,h}'
   ext.ext_dir = File.join('src', 'ruby', 'ext', 'grpc')
   ext.lib_dir = File.join('src', 'ruby', 'lib', 'grpc')
diff --git a/test/distrib/ruby/run_distrib_test.sh b/test/distrib/ruby/run_distrib_test.sh
index 99fb873589c..cb2eb1ff7d5 100755
--- a/test/distrib/ruby/run_distrib_test.sh
+++ b/test/distrib/ruby/run_distrib_test.sh
@@ -35,3 +35,24 @@ gem generate_index --directory "${GEM_SOURCE}"
 bundle install
 
 bundle exec ./distribtest.rb
+
+# Attempt to repro https://github.com/google/protobuf/issues/4210.
+# TODO: This sanity check only works for linux-based distrib tests and for
+# binary gRPC packages. It will need to be ran conditionally if this test script is
+# used for other types of distrib tests.
+INSTALLATION_DIR="$(gem env | grep '\- INSTALLATION DIRECTORY' | awk '{ print $4 }')"
+if [[ "$(find "$INSTALLATION_DIR" -name 'grpc_c.so' | wc -l)" == 0 ]]; then
+  echo "Sanity check failed. The gRPC package is not installed in $INSTALLATION_DIR."
+  exit 1
+fi
+LIBRUBY_DEPENDENCY_EXISTS="$(find "$INSTALLATION_DIR" -name 'grpc_c.so' -exec ldd {} \; | grep -c 'libruby')" || true
+if [[ "$LIBRUBY_DEPENDENCY_EXISTS" != 0 ]]; then
+  echo "A grpc_c.so file in this binary gRPC package is dynamically linked to libruby."
+fi
+DEPENDENCY_NOT_FOUND="$(find "$INSTALLATION_DIR" -name 'grpc_c.so' -exec ldd {} \; | grep -c 'not found')" || true
+if [[ "$DEPENDENCY_NOT_FOUND" != 0 ]]; then
+  echo "A grpc_c.so file in this binary gRPC package has an non-portable dependency."
+fi
+if [ "$LIBRUBY_DEPENDENCY_EXISTS" != 0 ] || [ "$DEPENDENCY_NOT_FOUND" != 0 ]; then
+  exit 1
+fi
diff --git a/tools/dockerfile/distribtest/ruby_fedora20_x64/Dockerfile b/tools/dockerfile/distribtest/ruby_fedora20_x64/Dockerfile
index 5ea51214fa4..200c5c28033 100644
--- a/tools/dockerfile/distribtest/ruby_fedora20_x64/Dockerfile
+++ b/tools/dockerfile/distribtest/ruby_fedora20_x64/Dockerfile
@@ -14,6 +14,6 @@
 
 FROM fedora:20
 
-RUN yum clean all && yum update -y && yum install -y ruby
+RUN yum clean all && yum update -y && yum install -y ruby findutils
 
 RUN gem install bundler
diff --git a/tools/dockerfile/distribtest/ruby_fedora21_x64/Dockerfile b/tools/dockerfile/distribtest/ruby_fedora21_x64/Dockerfile
index b90340119be..e1177fd99af 100644
--- a/tools/dockerfile/distribtest/ruby_fedora21_x64/Dockerfile
+++ b/tools/dockerfile/distribtest/ruby_fedora21_x64/Dockerfile
@@ -19,6 +19,6 @@ FROM fedora:21
 # https://github.com/docker/docker/issues/10180
 RUN yum install -y yum-plugin-ovl
 
-RUN yum clean all && yum update -y && yum install -y ruby
+RUN yum clean all && yum update -y && yum install -y ruby findutils
 
 RUN gem install bundler
diff --git a/tools/dockerfile/distribtest/ruby_fedora22_x64/Dockerfile b/tools/dockerfile/distribtest/ruby_fedora22_x64/Dockerfile
index 0d57370f863..848c5be789a 100644
--- a/tools/dockerfile/distribtest/ruby_fedora22_x64/Dockerfile
+++ b/tools/dockerfile/distribtest/ruby_fedora22_x64/Dockerfile
@@ -14,6 +14,6 @@
 
 FROM fedora:22
 
-RUN yum clean all && yum update -y && yum install -y ruby
+RUN yum clean all && yum update -y && yum install -y ruby findutils
 
 RUN gem install bundler
diff --git a/tools/dockerfile/distribtest/ruby_fedora23_x64/Dockerfile b/tools/dockerfile/distribtest/ruby_fedora23_x64/Dockerfile
index 318993b0739..47dd577e217 100644
--- a/tools/dockerfile/distribtest/ruby_fedora23_x64/Dockerfile
+++ b/tools/dockerfile/distribtest/ruby_fedora23_x64/Dockerfile
@@ -14,6 +14,6 @@
 
 FROM fedora:23
 
-RUN yum clean all && yum update -y && yum install -y ruby
+RUN yum clean all && yum update -y && yum install -y ruby findutils
 
 RUN gem install bundler