diff --git a/src/core/ext/filters/client_channel/client_channel.cc b/src/core/ext/filters/client_channel/client_channel.cc
index 38131907942..fa0c280f801 100644
--- a/src/core/ext/filters/client_channel/client_channel.cc
+++ b/src/core/ext/filters/client_channel/client_channel.cc
@@ -3242,7 +3242,7 @@ static void on_external_watch_complete_locked(void* arg, grpc_error* error) {
                            "external_connectivity_watcher");
   external_connectivity_watcher_list_remove(w->chand, w);
   gpr_free(w);
-  GRPC_CLOSURE_RUN(follow_up, GRPC_ERROR_REF(error));
+  GRPC_CLOSURE_SCHED(follow_up, GRPC_ERROR_REF(error));
 }
 
 static void watch_connectivity_state_locked(void* arg,
diff --git a/src/core/ext/filters/client_channel/subchannel.cc b/src/core/ext/filters/client_channel/subchannel.cc
index 140441da108..ad6b6dd1920 100644
--- a/src/core/ext/filters/client_channel/subchannel.cc
+++ b/src/core/ext/filters/client_channel/subchannel.cc
@@ -408,7 +408,7 @@ static void on_external_state_watcher_done(void* arg, grpc_error* error) {
   gpr_mu_unlock(&w->subchannel->mu);
   GRPC_SUBCHANNEL_WEAK_UNREF(w->subchannel, "external_state_watcher");
   gpr_free(w);
-  GRPC_CLOSURE_RUN(follow_up, GRPC_ERROR_REF(error));
+  GRPC_CLOSURE_SCHED(follow_up, GRPC_ERROR_REF(error));
 }
 
 static void on_alarm(void* arg, grpc_error* error) {
diff --git a/src/core/ext/transport/chttp2/transport/chttp2_transport.cc b/src/core/ext/transport/chttp2/transport/chttp2_transport.cc
index 7ff7cabfbd0..cc4a8237981 100644
--- a/src/core/ext/transport/chttp2/transport/chttp2_transport.cc
+++ b/src/core/ext/transport/chttp2/transport/chttp2_transport.cc
@@ -1684,16 +1684,16 @@ static void send_ping_locked(grpc_chttp2_transport* t,
  */
 static void send_keepalive_ping_locked(grpc_chttp2_transport* t) {
   if (t->closed_with_error != GRPC_ERROR_NONE) {
-    GRPC_CLOSURE_SCHED(&t->start_keepalive_ping_locked,
-                       GRPC_ERROR_REF(t->closed_with_error));
-    GRPC_CLOSURE_SCHED(&t->finish_keepalive_ping_locked,
-                       GRPC_ERROR_REF(t->closed_with_error));
+    GRPC_CLOSURE_RUN(&t->start_keepalive_ping_locked,
+                     GRPC_ERROR_REF(t->closed_with_error));
+    GRPC_CLOSURE_RUN(&t->finish_keepalive_ping_locked,
+                     GRPC_ERROR_REF(t->closed_with_error));
     return;
   }
   grpc_chttp2_ping_queue* pq = &t->ping_queue;
   if (!grpc_closure_list_empty(pq->lists[GRPC_CHTTP2_PCL_INFLIGHT])) {
     /* There is a ping in flight. Add yourself to the inflight closure list. */
-    GRPC_CLOSURE_SCHED(&t->start_keepalive_ping_locked, GRPC_ERROR_NONE);
+    GRPC_CLOSURE_RUN(&t->start_keepalive_ping_locked, GRPC_ERROR_NONE);
     grpc_closure_list_append(&pq->lists[GRPC_CHTTP2_PCL_INFLIGHT],
                              &t->finish_keepalive_ping_locked, GRPC_ERROR_NONE);
     return;
diff --git a/src/core/lib/iomgr/combiner.cc b/src/core/lib/iomgr/combiner.cc
index 9429842eb85..6789e4d12db 100644
--- a/src/core/lib/iomgr/combiner.cc
+++ b/src/core/lib/iomgr/combiner.cc
@@ -63,11 +63,12 @@ struct grpc_combiner {
   gpr_refcount refs;
 };
 
+static void combiner_run(grpc_closure* closure, grpc_error* error);
 static void combiner_exec(grpc_closure* closure, grpc_error* error);
 static void combiner_finally_exec(grpc_closure* closure, grpc_error* error);
 
 static const grpc_closure_scheduler_vtable scheduler = {
-    combiner_exec, combiner_exec, "combiner:immediately"};
+    combiner_run, combiner_exec, "combiner:immediately"};
 static const grpc_closure_scheduler_vtable finally_scheduler = {
     combiner_finally_exec, combiner_finally_exec, "combiner:finally"};
 
@@ -343,6 +344,22 @@ static void combiner_finally_exec(grpc_closure* closure, grpc_error* error) {
   grpc_closure_list_append(&lock->final_list, closure, error);
 }
 
+static void combiner_run(grpc_closure* closure, grpc_error* error) {
+  grpc_combiner* lock = COMBINER_FROM_CLOSURE_SCHEDULER(closure, scheduler);
+#ifndef NDEBUG
+  closure->scheduled = false;
+  GRPC_COMBINER_TRACE(gpr_log(
+      GPR_DEBUG,
+      "Combiner:%p grpc_combiner_run closure:%p created [%s:%d] run [%s:%d]",
+      lock, closure, closure->file_created, closure->line_created,
+      closure->file_initiated, closure->line_initiated));
+#endif
+  GPR_ASSERT(grpc_core::ExecCtx::Get()->combiner_data()->active_combiner ==
+             lock);
+  closure->cb(closure->cb_arg, error);
+  GRPC_ERROR_UNREF(error);
+}
+
 static void enqueue_finally(void* closure, grpc_error* error) {
   combiner_finally_exec(static_cast<grpc_closure*>(closure),
                         GRPC_ERROR_REF(error));
diff --git a/src/core/lib/iomgr/resource_quota.cc b/src/core/lib/iomgr/resource_quota.cc
index 8cf4fe99282..539bc120cec 100644
--- a/src/core/lib/iomgr/resource_quota.cc
+++ b/src/core/lib/iomgr/resource_quota.cc
@@ -386,7 +386,7 @@ static bool rq_reclaim(grpc_resource_quota* resource_quota, bool destructive) {
   resource_quota->debug_only_last_reclaimer_resource_user = resource_user;
   resource_quota->debug_only_last_initiated_reclaimer = c;
   resource_user->reclaimers[destructive] = nullptr;
-  GRPC_CLOSURE_RUN(c, GRPC_ERROR_NONE);
+  GRPC_CLOSURE_SCHED(c, GRPC_ERROR_NONE);
   return true;
 }
 
diff --git a/src/core/lib/iomgr/tcp_custom.cc b/src/core/lib/iomgr/tcp_custom.cc
index b3b29340146..990e8d632b9 100644
--- a/src/core/lib/iomgr/tcp_custom.cc
+++ b/src/core/lib/iomgr/tcp_custom.cc
@@ -141,7 +141,7 @@ static void call_read_cb(custom_tcp_endpoint* tcp, grpc_error* error) {
   TCP_UNREF(tcp, "read");
   tcp->read_slices = nullptr;
   tcp->read_cb = nullptr;
-  GRPC_CLOSURE_RUN(cb, error);
+  GRPC_CLOSURE_SCHED(cb, error);
 }
 
 static void custom_read_callback(grpc_custom_socket* socket, size_t nread,
diff --git a/src/core/lib/iomgr/tcp_posix.cc b/src/core/lib/iomgr/tcp_posix.cc
index 153be05e83c..b79ffe20f1a 100644
--- a/src/core/lib/iomgr/tcp_posix.cc
+++ b/src/core/lib/iomgr/tcp_posix.cc
@@ -366,7 +366,7 @@ static void call_read_cb(grpc_tcp* tcp, grpc_error* error) {
 
   tcp->read_cb = nullptr;
   tcp->incoming_buffer = nullptr;
-  GRPC_CLOSURE_RUN(cb, error);
+  GRPC_CLOSURE_SCHED(cb, error);
 }
 
 #define MAX_READ_IOVEC 4
@@ -629,7 +629,7 @@ static void tcp_handle_write(void* arg /* grpc_tcp */, grpc_error* error) {
       gpr_log(GPR_INFO, "write: %s", str);
     }
 
-    GRPC_CLOSURE_RUN(cb, error);
+    GRPC_CLOSURE_SCHED(cb, error);
     TCP_UNREF(tcp, "write");
   }
 }
diff --git a/src/core/lib/surface/call.cc b/src/core/lib/surface/call.cc
index da488034ca9..7ed1696f802 100644
--- a/src/core/lib/surface/call.cc
+++ b/src/core/lib/surface/call.cc
@@ -1259,8 +1259,12 @@ static void post_batch_completion(batch_control* bctl) {
   if (bctl->completion_data.notify_tag.is_closure) {
     /* unrefs bctl->error */
     bctl->call = nullptr;
-    GRPC_CLOSURE_RUN((grpc_closure*)bctl->completion_data.notify_tag.tag,
-                     error);
+    /* This closure may be meant to be run within some combiner. Since we aren't
+     * running in any combiner here, we need to use GRPC_CLOSURE_SCHED instead
+     * of GRPC_CLOSURE_RUN.
+     */
+    GRPC_CLOSURE_SCHED((grpc_closure*)bctl->completion_data.notify_tag.tag,
+                       error);
     GRPC_CALL_INTERNAL_UNREF(call, "completion");
   } else {
     /* unrefs bctl->error */