diff --git a/src/csharp/Grpc.Core.Api/Grpc.Core.Api.csproj b/src/csharp/Grpc.Core.Api/Grpc.Core.Api.csproj
index e684cf8b55e..cc21a14c977 100755
--- a/src/csharp/Grpc.Core.Api/Grpc.Core.Api.csproj
+++ b/src/csharp/Grpc.Core.Api/Grpc.Core.Api.csproj
@@ -13,7 +13,7 @@
   </PropertyGroup>
 
   <PropertyGroup>
-    <TargetFrameworks>net45;netstandard1.5;netstandard2.0</TargetFrameworks>
+    <TargetFrameworks>net45;netstandard1.5;netstandard2.0;netstandard2.1</TargetFrameworks>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
diff --git a/src/csharp/Grpc.Core.Api/IAsyncStreamWriter.cs b/src/csharp/Grpc.Core.Api/IAsyncStreamWriter.cs
index b44eba02d02..717fa1eae94 100644
--- a/src/csharp/Grpc.Core.Api/IAsyncStreamWriter.cs
+++ b/src/csharp/Grpc.Core.Api/IAsyncStreamWriter.cs
@@ -20,6 +20,7 @@ using System;
 using System.Collections.Generic;
 using System.Linq;
 using System.Text;
+using System.Threading;
 using System.Threading.Tasks;
 
 namespace Grpc.Core
@@ -36,6 +37,26 @@ namespace Grpc.Core
         /// <param name="message">The message to be written. Cannot be null.</param>
         Task WriteAsync(T message);
 
+#if NETSTANDARD2_1_OR_GREATER
+        /// <summary>
+        /// Writes a message asynchronously. Only one write can be pending at a time.
+        /// </summary>
+        /// <param name="message">The message to be written. Cannot be null.</param>
+        /// <param name="cancellationToken">Cancellation token that can be used to cancel the operation.</param>
+        Task WriteAsync(T message, CancellationToken cancellationToken)
+        {
+            if (cancellationToken.CanBeCanceled)
+            {
+                // Note to implementors:
+                // Add a netstandard2.1 or greater target to your library and override
+                // WriteAsync(T, CancellationToken) on stream writer to use the cancellation token.
+                throw new NotSupportedException("Cancellation of stream writes is not supported by this gRPC implementation.");
+            }
+
+            return WriteAsync(message);
+        }
+#endif
+
         /// <summary>
         /// Write options that will be used for the next write.
         /// If null, default options will be used.