diff --git a/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj b/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
index 82fb080e6ef..18993a93e00 100755
--- a/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
+++ b/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.Core.Tests</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.Core.Tests</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.Examples.Tests/Grpc.Examples.Tests.csproj b/src/csharp/Grpc.Examples.Tests/Grpc.Examples.Tests.csproj
index 32362aad87b..3ccc9adfaf7 100755
--- a/src/csharp/Grpc.Examples.Tests/Grpc.Examples.Tests.csproj
+++ b/src/csharp/Grpc.Examples.Tests/Grpc.Examples.Tests.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.Examples.Tests</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.Examples.Tests</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.HealthCheck.Tests/Grpc.HealthCheck.Tests.csproj b/src/csharp/Grpc.HealthCheck.Tests/Grpc.HealthCheck.Tests.csproj
index a9920ff68ec..9da0539dcb9 100755
--- a/src/csharp/Grpc.HealthCheck.Tests/Grpc.HealthCheck.Tests.csproj
+++ b/src/csharp/Grpc.HealthCheck.Tests/Grpc.HealthCheck.Tests.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.HealthCheck.Tests</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.HealthCheck.Tests</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.IntegrationTesting.Client/Grpc.IntegrationTesting.Client.csproj b/src/csharp/Grpc.IntegrationTesting.Client/Grpc.IntegrationTesting.Client.csproj
index 0f3971e8d65..35713156ea2 100755
--- a/src/csharp/Grpc.IntegrationTesting.Client/Grpc.IntegrationTesting.Client.csproj
+++ b/src/csharp/Grpc.IntegrationTesting.Client/Grpc.IntegrationTesting.Client.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.IntegrationTesting.Client</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.IntegrationTesting.Client</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.IntegrationTesting.QpsWorker/Grpc.IntegrationTesting.QpsWorker.csproj b/src/csharp/Grpc.IntegrationTesting.QpsWorker/Grpc.IntegrationTesting.QpsWorker.csproj
index 92ed20b0395..3ecefe3bc4f 100755
--- a/src/csharp/Grpc.IntegrationTesting.QpsWorker/Grpc.IntegrationTesting.QpsWorker.csproj
+++ b/src/csharp/Grpc.IntegrationTesting.QpsWorker/Grpc.IntegrationTesting.QpsWorker.csproj
@@ -9,7 +9,6 @@
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.IntegrationTesting.QpsWorker</PackageId>
     <ServerGarbageCollection>true</ServerGarbageCollection>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.IntegrationTesting.Server/Grpc.IntegrationTesting.Server.csproj b/src/csharp/Grpc.IntegrationTesting.Server/Grpc.IntegrationTesting.Server.csproj
index 4480ca1bbaa..1092b2c21ef 100755
--- a/src/csharp/Grpc.IntegrationTesting.Server/Grpc.IntegrationTesting.Server.csproj
+++ b/src/csharp/Grpc.IntegrationTesting.Server/Grpc.IntegrationTesting.Server.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.IntegrationTesting.Server</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.IntegrationTesting.Server</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.IntegrationTesting.StressClient/Grpc.IntegrationTesting.StressClient.csproj b/src/csharp/Grpc.IntegrationTesting.StressClient/Grpc.IntegrationTesting.StressClient.csproj
index fef23633ccb..22272547f61 100755
--- a/src/csharp/Grpc.IntegrationTesting.StressClient/Grpc.IntegrationTesting.StressClient.csproj
+++ b/src/csharp/Grpc.IntegrationTesting.StressClient/Grpc.IntegrationTesting.StressClient.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.IntegrationTesting.StressClient</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.IntegrationTesting.StressClient</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.IntegrationTesting/Grpc.IntegrationTesting.csproj b/src/csharp/Grpc.IntegrationTesting/Grpc.IntegrationTesting.csproj
index b0de1dc560f..c02c9844e3d 100755
--- a/src/csharp/Grpc.IntegrationTesting/Grpc.IntegrationTesting.csproj
+++ b/src/csharp/Grpc.IntegrationTesting/Grpc.IntegrationTesting.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.IntegrationTesting</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.IntegrationTesting</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.Microbenchmarks/Grpc.Microbenchmarks.csproj b/src/csharp/Grpc.Microbenchmarks/Grpc.Microbenchmarks.csproj
index 0da24c6179d..108357e4eb4 100644
--- a/src/csharp/Grpc.Microbenchmarks/Grpc.Microbenchmarks.csproj
+++ b/src/csharp/Grpc.Microbenchmarks/Grpc.Microbenchmarks.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.Microbenchmarks</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.Microbenchmarks</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>
 
diff --git a/src/csharp/Grpc.Reflection.Tests/Grpc.Reflection.Tests.csproj b/src/csharp/Grpc.Reflection.Tests/Grpc.Reflection.Tests.csproj
index 33a9106caed..d3686971245 100755
--- a/src/csharp/Grpc.Reflection.Tests/Grpc.Reflection.Tests.csproj
+++ b/src/csharp/Grpc.Reflection.Tests/Grpc.Reflection.Tests.csproj
@@ -8,7 +8,6 @@
     <AssemblyName>Grpc.Reflection.Tests</AssemblyName>
     <OutputType>Exe</OutputType>
     <PackageId>Grpc.Reflection.Tests</PackageId>
-    <PackageTargetFallback Condition=" '$(TargetFramework)' == 'netcoreapp1.0' ">$(PackageTargetFallback);portable-net45</PackageTargetFallback>
     <TreatWarningsAsErrors>true</TreatWarningsAsErrors>
   </PropertyGroup>