diff --git a/src/csharp/Grpc.Core.Tests/MockServiceHelper.cs b/src/csharp/Grpc.Core.Tests/MockServiceHelper.cs
index 4d904700569..c57c260c960 100644
--- a/src/csharp/Grpc.Core.Tests/MockServiceHelper.cs
+++ b/src/csharp/Grpc.Core.Tests/MockServiceHelper.cs
@@ -141,7 +141,8 @@ namespace Grpc.Core.Tests
         {
             if (server == null)
             {
-                server = new Server
+                // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+                server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
                 {
                     Services = { serviceDefinition },
                     Ports = { { Host, ServerPort.PickUnused, ServerCredentials.Insecure } }
diff --git a/src/csharp/Grpc.Core/ChannelOptions.cs b/src/csharp/Grpc.Core/ChannelOptions.cs
index 46a2c6695f6..5de9b1ee3c4 100644
--- a/src/csharp/Grpc.Core/ChannelOptions.cs
+++ b/src/csharp/Grpc.Core/ChannelOptions.cs
@@ -172,6 +172,9 @@ namespace Grpc.Core
         /// <summary>Secondary user agent: goes at the end of the user-agent metadata</summary>
         public const string SecondaryUserAgentString = "grpc.secondary_user_agent";
 
+        /// <summary>If non-zero, allow the use of SO_REUSEPORT for server if it's available (default 1)</summary>
+        public const string SoReuseport = "grpc.so_reuseport";
+
         /// <summary>
         /// Creates native object for a collection of channel options.
         /// </summary>
diff --git a/src/csharp/Grpc.Examples.Tests/MathClientServerTests.cs b/src/csharp/Grpc.Examples.Tests/MathClientServerTests.cs
index 50dacc2eaaf..02bcd18cb55 100644
--- a/src/csharp/Grpc.Examples.Tests/MathClientServerTests.cs
+++ b/src/csharp/Grpc.Examples.Tests/MathClientServerTests.cs
@@ -55,7 +55,8 @@ namespace Math.Tests
         [TestFixtureSetUp]
         public void Init()
         {
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { Math.BindService(new MathServiceImpl()) },
                 Ports = { { Host, ServerPort.PickUnused, ServerCredentials.Insecure } }
diff --git a/src/csharp/Grpc.HealthCheck.Tests/HealthClientServerTest.cs b/src/csharp/Grpc.HealthCheck.Tests/HealthClientServerTest.cs
index 25a58fb3864..0ebc3c33700 100644
--- a/src/csharp/Grpc.HealthCheck.Tests/HealthClientServerTest.cs
+++ b/src/csharp/Grpc.HealthCheck.Tests/HealthClientServerTest.cs
@@ -57,7 +57,8 @@ namespace Grpc.HealthCheck.Tests
         {
             serviceImpl = new HealthServiceImpl();
 
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { Grpc.Health.V1.Health.BindService(serviceImpl) },
                 Ports = { { Host, ServerPort.PickUnused, ServerCredentials.Insecure } }
diff --git a/src/csharp/Grpc.IntegrationTesting/GeneratedServiceBaseTest.cs b/src/csharp/Grpc.IntegrationTesting/GeneratedServiceBaseTest.cs
index 4216dc1d6be..780a9b73047 100644
--- a/src/csharp/Grpc.IntegrationTesting/GeneratedServiceBaseTest.cs
+++ b/src/csharp/Grpc.IntegrationTesting/GeneratedServiceBaseTest.cs
@@ -54,7 +54,8 @@ namespace Grpc.IntegrationTesting
         [SetUp]
         public void Init()
         {
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { TestService.BindService(new UnimplementedTestServiceImpl()) },
                 Ports = { { Host, ServerPort.PickUnused, SslServerCredentials.Insecure } }
diff --git a/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs b/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
index 4960a53f92d..04f833fcf5e 100644
--- a/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
+++ b/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
@@ -56,7 +56,8 @@ namespace Grpc.IntegrationTesting
         [TestFixtureSetUp]
         public void Init()
         {
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { TestService.BindService(new TestServiceImpl()) },
                 Ports = { { Host, ServerPort.PickUnused, TestCredentials.CreateSslServerCredentials() } }
diff --git a/src/csharp/Grpc.IntegrationTesting/MetadataCredentialsTest.cs b/src/csharp/Grpc.IntegrationTesting/MetadataCredentialsTest.cs
index d55e658d949..ef63f530f68 100644
--- a/src/csharp/Grpc.IntegrationTesting/MetadataCredentialsTest.cs
+++ b/src/csharp/Grpc.IntegrationTesting/MetadataCredentialsTest.cs
@@ -56,7 +56,8 @@ namespace Grpc.IntegrationTesting
         [SetUp]
         public void Init()
         {
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { TestService.BindService(new FakeTestService()) },
                 Ports = { { Host, ServerPort.PickUnused, TestCredentials.CreateSslServerCredentials() } }
diff --git a/src/csharp/Grpc.IntegrationTesting/SslCredentialsTest.cs b/src/csharp/Grpc.IntegrationTesting/SslCredentialsTest.cs
index 377dad63f40..48ecc2344fc 100644
--- a/src/csharp/Grpc.IntegrationTesting/SslCredentialsTest.cs
+++ b/src/csharp/Grpc.IntegrationTesting/SslCredentialsTest.cs
@@ -67,7 +67,8 @@ namespace Grpc.IntegrationTesting
             var serverCredentials = new SslServerCredentials(new[] { keyCertPair }, rootCert, true);
             var clientCredentials = new SslCredentials(rootCert, keyCertPair);
 
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { TestService.BindService(new SslCredentialsTestServiceImpl()) },
                 Ports = { { Host, ServerPort.PickUnused, serverCredentials } }
diff --git a/src/csharp/Grpc.Reflection.Tests/ReflectionClientServerTest.cs b/src/csharp/Grpc.Reflection.Tests/ReflectionClientServerTest.cs
index 1d0845e276c..22edbed0402 100644
--- a/src/csharp/Grpc.Reflection.Tests/ReflectionClientServerTest.cs
+++ b/src/csharp/Grpc.Reflection.Tests/ReflectionClientServerTest.cs
@@ -58,7 +58,8 @@ namespace Grpc.Reflection.Tests
         {
             serviceImpl = new ReflectionServiceImpl(ServerReflection.Descriptor);
 
-            server = new Server
+            // Disable SO_REUSEPORT to prevent https://github.com/grpc/grpc/issues/10755
+            server = new Server(new[] { new ChannelOption(ChannelOptions.SoReuseport, 0) })
             {
                 Services = { ServerReflection.BindService(serviceImpl) },
                 Ports = { { Host, ServerPort.PickUnused, ServerCredentials.Insecure } }