diff --git a/CMakeLists.txt b/CMakeLists.txt
index 3ff1a7b135e..6c370c3ebd8 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -220,15 +220,41 @@ function(protobuf_generate_grpc_cpp)
   endforeach()
 endfunction()
 
+# These options allow users to enable or disable the building of the various
+# protoc plugins. For example, running CMake with
+# -DgRPC_BUILD_GRPC_CSHARP_PLUGIN=OFF will disable building the C# plugin.
+set(_gRPC_PLUGIN_LIST)
+option(gRPC_BUILD_GRPC_CPP_PLUGIN "Build grpc_cpp_plugin" ON)
+if (gRPC_BUILD_GRPC_CPP_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_cpp_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_CSHARP_PLUGIN "Build grpc_csharp_plugin" ON)
+if (gRPC_BUILD_GRPC_CSHARP_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_csharp_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_NODE_PLUGIN "Build grpc_node_plugin" ON)
+if (gRPC_BUILD_GRPC_NODE_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_node_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_OBJECTIVE_C_PLUGIN "Build grpc_objective_c_plugin" ON)
+if (gRPC_BUILD_GRPC_OBJECTIVE_C_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_objective_c_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_PHP_PLUGIN "Build grpc_php_plugin" ON)
+if (gRPC_BUILD_GRPC_PHP_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_php_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_PYTHON_PLUGIN "Build grpc_python_plugin" ON)
+if (gRPC_BUILD_GRPC_PYTHON_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_python_plugin)
+endif ()
+option(gRPC_BUILD_GRPC_RUBY_PLUGIN "Build grpc_ruby_plugin" ON)
+if (gRPC_BUILD_GRPC_RUBY_PLUGIN)
+  list(APPEND _gRPC_PLUGIN_LIST grpc_ruby_plugin)
+endif ()
+
 add_custom_target(plugins
-  DEPENDS
-  grpc_cpp_plugin
-  grpc_csharp_plugin
-  grpc_node_plugin
-  grpc_objective_c_plugin
-  grpc_php_plugin
-  grpc_python_plugin
-  grpc_ruby_plugin
+  DEPENDS ${_gRPC_PLUGIN_LIST}
 )
 
 add_custom_target(tools_c
@@ -12906,7 +12932,7 @@ target_link_libraries(grpc_cli
 
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_CPP_PLUGIN)
 
 add_executable(grpc_cpp_plugin
   src/compiler/cpp_plugin.cc
@@ -12943,7 +12969,7 @@ if(gRPC_INSTALL)
 endif()
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_CSHARP_PLUGIN)
 
 add_executable(grpc_csharp_plugin
   src/compiler/csharp_plugin.cc
@@ -13053,7 +13079,7 @@ target_link_libraries(grpc_linux_system_roots_test
 
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_NODE_PLUGIN)
 
 add_executable(grpc_node_plugin
   src/compiler/node_plugin.cc
@@ -13090,7 +13116,7 @@ if(gRPC_INSTALL)
 endif()
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_OBJECTIVE_C_PLUGIN)
 
 add_executable(grpc_objective_c_plugin
   src/compiler/objective_c_plugin.cc
@@ -13127,7 +13153,7 @@ if(gRPC_INSTALL)
 endif()
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_PHP_PLUGIN)
 
 add_executable(grpc_php_plugin
   src/compiler/php_plugin.cc
@@ -13164,7 +13190,7 @@ if(gRPC_INSTALL)
 endif()
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_PYTHON_PLUGIN)
 
 add_executable(grpc_python_plugin
   src/compiler/python_plugin.cc
@@ -13201,7 +13227,7 @@ if(gRPC_INSTALL)
 endif()
 
 endif()
-if(gRPC_BUILD_CODEGEN)
+if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_GRPC_RUBY_PLUGIN)
 
 add_executable(grpc_ruby_plugin
   src/compiler/ruby_plugin.cc
diff --git a/templates/CMakeLists.txt.template b/templates/CMakeLists.txt.template
index 923cda9b34c..998234972b7 100644
--- a/templates/CMakeLists.txt.template
+++ b/templates/CMakeLists.txt.template
@@ -315,13 +315,21 @@
     endforeach()
   endfunction()
 
-  add_custom_target(plugins
-    DEPENDS
+  # These options allow users to enable or disable the building of the various
+  # protoc plugins. For example, running CMake with
+  # -DgRPC_BUILD_GRPC_CSHARP_PLUGIN=OFF will disable building the C# plugin.
+  set(_gRPC_PLUGIN_LIST)
   % for tgt in targets:
   % if tgt.build == 'protoc':
-    ${tgt.name}
+  option(gRPC_BUILD_${tgt.name.upper()} "Build ${tgt.name}" ON)
+  if (gRPC_BUILD_${tgt.name.upper()})
+    list(APPEND _gRPC_PLUGIN_LIST ${tgt.name})
+  endif ()
   % endif
   % endfor
+
+  add_custom_target(plugins
+    DEPENDS <%text>${_gRPC_PLUGIN_LIST}</%text>
   )
 
   add_custom_target(tools_c
@@ -419,7 +427,7 @@
   </%block>
   endif()
   % elif tgt.build in ["protoc"]:
-  if(gRPC_BUILD_CODEGEN)
+  if(gRPC_BUILD_CODEGEN AND gRPC_BUILD_${tgt.name.upper()})
   <%block filter='platforms_condition_block(tgt.platforms)'>
   ${cc_binary(tgt)}
   ${cc_install(tgt)}