diff --git a/.gitignore b/.gitignore
index bcf82223bee..b08fa159e69 100644
--- a/.gitignore
+++ b/.gitignore
@@ -17,7 +17,7 @@ cython_debug/
 dist/
 htmlcov/
 py3*/
-python_build/
+pyb/
 python_pylint_venv/
 src/python/grpcio_*/=*
 src/python/grpcio_*/build/
diff --git a/setup.cfg b/setup.cfg
index 3ac6b513ae3..be9e83e43b0 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -4,7 +4,7 @@
 plugins = Cython.Coverage
 
 [build]
-build_base=python_build
+build_base=pyb
 
 [build_ext]
 inplace=1
diff --git a/src/python/grpcio/commands.py b/src/python/grpcio/commands.py
index 338dbd7d265..98324c955f9 100644
--- a/src/python/grpcio/commands.py
+++ b/src/python/grpcio/commands.py
@@ -349,7 +349,7 @@ class Clean(setuptools.Command):
     ]
 
     _FILE_PATTERNS = (
-        "python_build",
+        "pyb",
         "src/python/grpcio/__pycache__/",
         "src/python/grpcio/grpc/_cython/cygrpc.cpp",
         "src/python/grpcio/grpc/_cython/*.so",