diff --git a/src/core/lib/iomgr/tcp_server_posix.c b/src/core/lib/iomgr/tcp_server_posix.c
index 74ec32d4574..ea8d2411547 100644
--- a/src/core/lib/iomgr/tcp_server_posix.c
+++ b/src/core/lib/iomgr/tcp_server_posix.c
@@ -308,7 +308,7 @@ static grpc_error *prepare_socket(int fd, const struct sockaddr *addr,
 
   GPR_ASSERT(fd >= 0);
 
-  if (so_reuseport) {
+  if (so_reuseport && !grpc_is_unix_socket(addr)) {
     err = grpc_set_socket_reuse_port(fd, 1);
     if (err != GRPC_ERROR_NONE) goto error;
   }
@@ -693,7 +693,8 @@ void grpc_tcp_server_start(grpc_exec_ctx *exec_ctx, grpc_tcp_server *s,
   s->pollset_count = pollset_count;
   sp = s->head;
   while (sp != NULL) {
-    if (s->so_reuseport && pollset_count > 1) {
+    if (s->so_reuseport && !grpc_is_unix_socket(&sp->addr.sockaddr) &&
+        pollset_count > 1) {
       GPR_ASSERT(GRPC_LOG_IF_ERROR(
           "clone_port", clone_port(sp, (unsigned)(pollset_count - 1))));
       for (i = 0; i < pollset_count; i++) {