diff --git a/setup.py b/setup.py
index 90df0a1042e..3234353efad 100644
--- a/setup.py
+++ b/setup.py
@@ -17,6 +17,12 @@
 # undesirable behaviors or errors.
 import setuptools
 
+# Monkey Patch the unix compiler to accept ASM
+# files used by boring SSL.
+from distutils.unixccompiler import UnixCCompiler
+UnixCCompiler.src_extensions.append('.S')
+del UnixCCompiler
+
 from distutils import cygwinccompiler
 from distutils import extension as _extension
 from distutils import util
@@ -97,6 +103,9 @@ CLASSIFIERS = [
     'License :: OSI Approved :: Apache Software License',
 ]
 
+BUILD_WITH_BORING_SSL_ASM = os.environ.get('GRPC_BUILD_WITH_BORING_SSL_ASM',
+                                           True)
+
 # Environment variable to determine whether or not the Cython extension should
 # *use* Cython or use the generated C files. Note that this requires the C files
 # to have been generated by building first *with* Cython support. Even if this
@@ -261,9 +270,30 @@ if BUILD_WITH_SYSTEM_ZLIB:
 if BUILD_WITH_SYSTEM_CARES:
     EXTENSION_LIBRARIES += ('cares',)
 
-DEFINE_MACROS = (('OPENSSL_NO_ASM', 1), ('_WIN32_WINNT', 0x600))
+DEFINE_MACROS = (('_WIN32_WINNT', 0x600),)
+asm_files = []
+
+asm_key = ''
+if BUILD_WITH_BORING_SSL_ASM:
+    LINUX_X86_64 = 'linux-x86_64'
+    LINUX_ARM = 'linux-arm'
+    if LINUX_X86_64 == util.get_platform():
+        asm_key = 'crypto_linux_x86_64'
+    elif LINUX_ARM == util.get_platform():
+        asm_key = 'crypto_linux_arm'
+    elif "mac" in util.get_platform() and "x86_64" in util.get_platform():
+        asm_key = 'crypto_mac_x86_64'
+    else:
+        print("ASM Builds for BoringSSL currently not supported on:",
+              util.get_platform())
+if asm_key:
+    asm_files = grpc_core_dependencies.ASM_SOURCE_FILES[asm_key]
+else:
+    DEFINE_MACROS += (('OPENSSL_NO_ASM', 1),)
+
 if not DISABLE_LIBC_COMPATIBILITY:
     DEFINE_MACROS += (('GPR_BACKWARDS_COMPATIBILITY_MODE', 1),)
+
 if "win32" in sys.platform:
     # TODO(zyc): Re-enable c-ares on x64 and x86 windows after fixing the
     # ares_library_init compilation issue
@@ -328,7 +358,8 @@ def cython_extensions_and_necessity():
     extensions = [
         _extension.Extension(
             name=module_name,
-            sources=[module_file] + list(CYTHON_HELPER_C_FILES) + core_c_files,
+            sources=([module_file] + list(CYTHON_HELPER_C_FILES) +
+                     core_c_files + asm_files),
             include_dirs=list(EXTENSION_INCLUDE_DIRECTORIES),
             libraries=list(EXTENSION_LIBRARIES),
             define_macros=list(DEFINE_MACROS),
diff --git a/src/boringssl/gen_build_yaml.py b/src/boringssl/gen_build_yaml.py
index 0b869fa64f3..1b77fedad01 100755
--- a/src/boringssl/gen_build_yaml.py
+++ b/src/boringssl/gen_build_yaml.py
@@ -46,6 +46,10 @@ class Grpc(object):
 
     def WriteFiles(self, files):
         test_binaries = ['ssl_test', 'crypto_test']
+        asm_outputs = {
+            key: value for key, value in files.items() if any(
+                f.endswith(".S") or f.endswith(".asm") for f in value)
+        }
         self.yaml = {
             '#':
                 'generated with src/boringssl/gen_build_yaml.py',
@@ -65,6 +69,10 @@ class Grpc(object):
                     'src':
                         sorted(
                             map_dir(f) for f in files['ssl'] + files['crypto']),
+                    'asm_src': {
+                        k: [map_dir(f) for f in value
+                           ] for k, value in asm_outputs.items()
+                    },
                     'headers':
                         sorted(
                             map_dir(f)
diff --git a/src/python/grpcio/grpc_core_dependencies.py b/src/python/grpcio/grpc_core_dependencies.py
index b0647cb5cd1..f91a68f50ef 100644
--- a/src/python/grpcio/grpc_core_dependencies.py
+++ b/src/python/grpcio/grpc_core_dependencies.py
@@ -911,3 +911,172 @@ CORE_SOURCE_FILES = [
     'third_party/zlib/uncompr.c',
     'third_party/zlib/zutil.c',
 ]
+
+ASM_SOURCE_FILES = {
+    'crypto_ios_aarch64': [
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/chacha/chacha-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/test/trampoline-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/aesv8-armx64.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/armv8-mont.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/ghashv8-armx64.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/ghash-neon-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/sha1-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/sha256-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/sha512-armv8.S',
+        'third_party/boringssl-with-bazel/ios-aarch64/crypto/fipsmodule/vpaes-armv8.S',
+    ],
+    'crypto_mac_x86_64': [
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/chacha/chacha-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/cipher_extra/aes128gcmsiv-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/cipher_extra/chacha20_poly1305_x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/test/trampoline-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/aesni-gcm-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/aesni-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/ghash-ssse3-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/ghash-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/md5-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/p256-x86_64-asm.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/p256_beeu-x86_64-asm.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/rdrand-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/rsaz-avx2.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/sha1-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/sha256-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/sha512-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/vpaes-x86_64.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/x86_64-mont5.S',
+        'third_party/boringssl-with-bazel/mac-x86_64/crypto/fipsmodule/x86_64-mont.S',
+    ],
+    'crypto_win_x86': [
+        'third_party/boringssl-with-bazel/win-x86/crypto/chacha/chacha-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/test/trampoline-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/aesni-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/bn-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/co-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/ghash-ssse3-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/ghash-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/md5-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/sha1-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/sha256-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/sha512-586.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/vpaes-x86.asm',
+        'third_party/boringssl-with-bazel/win-x86/crypto/fipsmodule/x86-mont.asm',
+    ],
+    'crypto_linux_ppc64le': [
+        'third_party/boringssl-with-bazel/linux-ppc64le/crypto/test/trampoline-ppc.S',
+        'third_party/boringssl-with-bazel/linux-ppc64le/crypto/fipsmodule/aesp8-ppc.S',
+        'third_party/boringssl-with-bazel/linux-ppc64le/crypto/fipsmodule/ghashp8-ppc.S',
+    ],
+    'crypto_mac_x86': [
+        'third_party/boringssl-with-bazel/mac-x86/crypto/chacha/chacha-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/test/trampoline-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/aesni-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/bn-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/co-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/ghash-ssse3-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/ghash-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/md5-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/sha1-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/sha256-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/sha512-586.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/vpaes-x86.S',
+        'third_party/boringssl-with-bazel/mac-x86/crypto/fipsmodule/x86-mont.S',
+    ],
+    'crypto_linux_x86': [
+        'third_party/boringssl-with-bazel/linux-x86/crypto/chacha/chacha-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/test/trampoline-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/aesni-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/bn-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/co-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/ghash-ssse3-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/ghash-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/md5-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/sha1-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/sha256-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/sha512-586.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/vpaes-x86.S',
+        'third_party/boringssl-with-bazel/linux-x86/crypto/fipsmodule/x86-mont.S',
+    ],
+    'crypto_ios_arm': [
+        'third_party/boringssl-with-bazel/ios-arm/crypto/chacha/chacha-armv4.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/test/trampoline-armv4.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/aesv8-armx32.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/armv4-mont.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/bsaes-armv7.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/ghash-armv4.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/ghashv8-armx32.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/sha1-armv4-large.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/sha256-armv4.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/sha512-armv4.S',
+        'third_party/boringssl-with-bazel/ios-arm/crypto/fipsmodule/vpaes-armv7.S',
+    ],
+    'crypto_linux_x86_64': [
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/chacha/chacha-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/cipher_extra/aes128gcmsiv-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/cipher_extra/chacha20_poly1305_x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/test/trampoline-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/aesni-gcm-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/aesni-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/ghash-ssse3-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/ghash-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/md5-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/p256-x86_64-asm.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/p256_beeu-x86_64-asm.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/rdrand-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/rsaz-avx2.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/sha1-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/sha256-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/sha512-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/vpaes-x86_64.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/x86_64-mont5.S',
+        'third_party/boringssl-with-bazel/linux-x86_64/crypto/fipsmodule/x86_64-mont.S',
+        'third_party/boringssl-with-bazel/src/crypto/hrss/asm/poly_rq_mul.S',
+    ],
+    'crypto_win_x86_64': [
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/chacha/chacha-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/cipher_extra/aes128gcmsiv-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/cipher_extra/chacha20_poly1305_x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/test/trampoline-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/aesni-gcm-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/aesni-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/ghash-ssse3-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/ghash-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/md5-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/p256-x86_64-asm.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/p256_beeu-x86_64-asm.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/rdrand-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/rsaz-avx2.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/sha1-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/sha256-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/sha512-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/vpaes-x86_64.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/x86_64-mont5.asm',
+        'third_party/boringssl-with-bazel/win-x86_64/crypto/fipsmodule/x86_64-mont.asm',
+    ],
+    'crypto_linux_aarch64': [
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/chacha/chacha-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/test/trampoline-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/aesv8-armx64.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/armv8-mont.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/ghashv8-armx64.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/ghash-neon-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/sha1-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/sha256-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/sha512-armv8.S',
+        'third_party/boringssl-with-bazel/linux-aarch64/crypto/fipsmodule/vpaes-armv8.S',
+    ],
+    'crypto_linux_arm': [
+        'third_party/boringssl-with-bazel/linux-arm/crypto/chacha/chacha-armv4.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/test/trampoline-armv4.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/aesv8-armx32.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/armv4-mont.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/bsaes-armv7.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/ghash-armv4.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/ghashv8-armx32.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/sha1-armv4-large.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/sha256-armv4.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/sha512-armv4.S',
+        'third_party/boringssl-with-bazel/linux-arm/crypto/fipsmodule/vpaes-armv7.S',
+        'third_party/boringssl-with-bazel/src/crypto/curve25519/asm/x25519-asm-arm.S',
+        'third_party/boringssl-with-bazel/src/crypto/poly1305/poly1305_arm_asm.S',
+    ],
+}
diff --git a/templates/src/python/grpcio/grpc_core_dependencies.py.template b/templates/src/python/grpcio/grpc_core_dependencies.py.template
index a62b54e45b0..153e7f8aef8 100644
--- a/templates/src/python/grpcio/grpc_core_dependencies.py.template
+++ b/templates/src/python/grpcio/grpc_core_dependencies.py.template
@@ -17,10 +17,13 @@
   # AUTO-GENERATED FROM `$REPO_ROOT/templates/src/python/grpcio/grpc_core_dependencies.py.template`!!!
   <%
     srcs = []
+    asm_srcs = {}
     for lib in libs:
       if lib.name in python_dependencies.transitive_deps:
         for src in lib.src:
           srcs.append(src)
+      if hasattr(lib, 'asm_src'):
+        asm_srcs = lib.asm_src
     srcs = sorted(set(srcs))
   %>
   CORE_SOURCE_FILES = [
@@ -28,3 +31,13 @@
       '${src}',
   % endfor
   ]
+
+  ASM_SOURCE_FILES = {
+  % for asm, asm_src in asm_srcs.iteritems():
+      '${asm}': [
+    % for src in asm_src:
+          '${src}',
+    % endfor
+      ],
+  % endfor
+  }
diff --git a/tools/buildgen/plugins/check_attrs.py b/tools/buildgen/plugins/check_attrs.py
index 467406f4b93..a9acd1ea550 100644
--- a/tools/buildgen/plugins/check_attrs.py
+++ b/tools/buildgen/plugins/check_attrs.py
@@ -38,6 +38,7 @@ VALID_ATTRIBUTE_KEYS_MAP = {
         'uses': anything(),
     },
     'lib': {
+        'asm_src': anything(),
         'baselib': anything(),
         'boringssl': one_of((True,)),
         'build_system': anything(),
diff --git a/tools/run_tests/artifacts/build_artifact_python.sh b/tools/run_tests/artifacts/build_artifact_python.sh
index a2b2542ac2b..abd6900152c 100755
--- a/tools/run_tests/artifacts/build_artifact_python.sh
+++ b/tools/run_tests/artifacts/build_artifact_python.sh
@@ -53,6 +53,7 @@ clean_non_source_files() {
     | grep -v '\.c$' | grep -v '\.cc$' | grep -v '\.cpp$' \
     | grep -v '\.h$' | grep -v '\.hh$' | grep -v '\.inc$' \
     | grep -v '\.s$' | grep -v '\.py$' | grep -v '\.hpp$' \
+    | grep -v '\.S$' | grep -v '\.asm$'                   \
     | while read -r file; do
       rm -f "$file" || true
     done