diff --git a/tools/interop_matrix/client_matrix.py b/tools/interop_matrix/client_matrix.py
index 3f130753084..e640bc2c71f 100644
--- a/tools/interop_matrix/client_matrix.py
+++ b/tools/interop_matrix/client_matrix.py
@@ -280,7 +280,7 @@ LANG_RELEASE_MATRIX = {
             ('v1.42.1', ReleaseInfo()),
             ('v1.43.2', ReleaseInfo()),
             ('v1.44.1', ReleaseInfo()),
-            ('v1.45.0', ReleaseInfo()),
+            ('v1.45.1', ReleaseInfo()),
         ]),
     'python':
         OrderedDict(