diff --git a/setup_once.h b/setup_once.h
index 99367aaa..de6c632b 100644
--- a/setup_once.h
+++ b/setup_once.h
@@ -297,7 +297,7 @@ typedef int sig_atomic_t;
  * Macro used to include code only in debug builds.
  */
 
-#ifdef CURLDEBUG
+#ifdef DEBUGBUILD
 #define DEBUGF(x) x
 #else
 #define DEBUGF(x) do { } while (0)
@@ -308,7 +308,7 @@ typedef int sig_atomic_t;
  * Macro used to include assertion code only in debug builds.
  */
 
-#if defined(CURLDEBUG) && defined(HAVE_ASSERT_H)
+#if defined(DEBUGBUILD) && defined(HAVE_ASSERT_H)
 #define DEBUGASSERT(x) assert(x)
 #else
 #define DEBUGASSERT(x) do { } while (0)